An anti-amyloid antibody drug that reduces amyloid beta proteins in the brain has provided a novel treatment for Alzheimer’s disease. This innovative brain imaging solution for Alzheimer’s disease management can analyze Amyloid-Related Imaging Abnormalities (ARIA), a known side-effect in patients using the anti-amyloid drug. Previously, careful monitoring and management of ARIA was crucial due to the drug’s side effects. 

An Artificial Intelligence (AI) company, Neurophet, specializes in brain diseases. Neurophet has created a new technology that examines ARIA-E (edema), generally detected by T2-FLAIR, and MRI sequence, along with ARIA-H (hemorrhages), mostly recognized by GRE or SWI. To properly observe cortical amyloid beta deposition, an amyloid-PET scan is essential. 

The AI technology developed by Neurophet predicts amyloid positivity through Magnetic Resonance (MR) images before conducting amyloid-PET scans. Since amyloid-PET scans are expensive and their use and recompense are severely restricted, the use of MR images for predicting amyloid positivity could offer a cost-effective solution in regards to clinical trials and prognosis of Alzheimer’s. 

Neurophet set the stage at the 2023 Alzheimer’s Association International Conference (AAIC) with its cutting-edge brain imaging analysis technology, which can be used in both clinical trials and Alzheimer’s disease drug prescriptions. 

AQUA software, a brain MRI analysis tool, examines brain atrophy observed in neurodegenerative diseases such as Alzheimer’s by measuring cortical amyloid beta deposition, a known causative agent of the disease. Neurophet hopes to bring the products to market side-by-side with new Alzheimer’s disease treatments. The company has invested in research and development focused on ARIA side effects. 

Jake Junkil Been, CEO of Neurophet, said, “Neurophet’s major products and technologies are expected to be very useful in the process of clinical trials, diagnosis, side effect monitoring, and prognosis observation of Alzheimer’s disease treatment. We are going all out to develop solutions related to Alzheimer’s disease treatment to preemptively target the high-growth Alzheimer’s disease treatment market.” 


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Written by the digital marketing team at Creative Programs & Systems: 

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