Surgeons at Michigan’s Henry Ford Health System successfully treated a patient who suffers from a recurrent brain tumor by delivering a dose of radiation therapy directly on the tumor. This new approach could revolutionize treatment by delaying or preventing future tumor cells from regrowing. Called GammaTile Therapy, the surgically targeted radiation therapy was the first of its kind performed in Michigan; the patient was a 41-year-old male.

Adam Robin, M.D., a neurosurgeon at the Hermelin Brain Tumor Center at Henry Ford, said, “The current standard of care for brain tumors is tumor resection, often followed by radiation, chemotherapy, or a combination of both. Approximately half of patients treated for brain tumors experience tumor recurrence within a year. In his most recent surgery, the patient was treated with a form of surgically targeted radiation therapy, which targets residual tumor cells with radiation before they can significantly replicate. Our hope is this therapy will delay or prevent the tumor cells from replicating and forming a recurrent tumor.”

GammaTile Therapy is cleared by the FDA and designed to delay tumor regrowth while protecting healthy brain tissue in patients who suffer from recurring tumors.

Mira M. Shah, M.D., a radiation oncologist at Henry Ford, external beam radiation therapy is usually delivered no sooner than two- to three weeks after surgery to let the incision heal. With GammaTile, the radiation is focused on specific areas of the brain using a type of brachytherapy (internal radiation) which delivers a therapeutic dose to the tumor during surgery.

Leaving the healthy tissue unharmed, GammaTile maximizes the amount of radiation aimed at the tumor and is critical for those patients who have received external beam radiation therapy, which exposes healthy tissue to radiation.

A bioresorbable, conformable 3D-collaten tile uses uniformly spaced radiation sources to target the tumor cavity after the tumor is removed. In just 33 days, 90 percent of the radiation dose is delivered, and after 100 days, the GammaTiles are considered free from radiation. The placement of GammaTile takes approximately five minutes.

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